Folate is impaired in autism, as this new study confirms, finding 84% have genetic deficiencies in its metabolism: Another 30-80% with autism have antibodies that impair folate's transport into the brain, and folinic acid (the newly approved Leucovorin) bypasses that antibody impairment
Chen, Y
Its primary mechanism involves activation of adenosine monophosphate-activated protein kinase (AMPK), sometimes described as the body's "metabolic master switch"
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